Radiation protection for emerging Targeted Alpha Therapies
16th April 2026
An example of a customized workstation installed at a research facility handling 225Ac.
At a glance
> Targeted Alpha Therapies present inherent radiation risks to facilities working in this rapidly growing area of clinical research.
> As a specialist manufacturer of custom-made shielding, BriTec can help keep those working with alpha-emitting radionuclides safe.
> Our cabinets, workstations and dispensing units can be customized to exact specifications, allowing new or existing facilities to be safeguarded.
BriTec’s shielding solutions allow facilities to safely handle alpha-emitting radionuclides
The rise of Targeted Alpha Therapies (TAT) is opening up promising new pathways for treating many critical illnesses, including cancers. But using powerful alpha-emitting radionuclides such as 225Ac, 211At and 212Pb present unique challenges for facilities handling, dispensing and storing them due to complex decay chains and associated radiation.
Although many alpha-emitting radionuclides such as 225Ac emit gammas during decay from daughters including 221Fr and 213Bi, the emissions are generally low in abundance. Nonetheless, appropriate shielding is critical to ensure staff safety.
Customized shielding for all energies
BriTec is a specialist manufacturer of shielded solutions for radiation protection based in the UK, with its machine workshop in Sheffield. With years of experience supplying medical and research facilities working with radioisotopes for diagnostics and therapies, BriTec has developed extensive expertise in shielding against gamma-emitting radionuclides and other higher energy isotopes, expertise that can now be applied to new alpha therapeutics.
For isotopes such as 212Pb which emit high-energy gammas, BriTec can supply customized shielding designed specifically for your requirements to safeguard against these emissions.
Complete project management from design to installation
BriTec has supplied both new facilities and existing ones undergoing refurbishment, collaborating closely with contractors to manage projects from concept to completion. As Targeted Alpha Therapies move from research to clinical use, it is critically important for sites to be futureproofed. As a precision manufacturer, BriTec can supply any custom-made designs made to detailed specifications as outlined by the end user, including:
- Workstations for safe handling and dispensing of alpha emitters.
- Storage units for securely storing radioactive materials such as lockable safes, cabinets and waste containers.
- Customized units tailored to exact dimensions to maximize space and optimize working arrangements.
Find out more
You can learn more about BriTec’s tailored solutions for Targeted Alpha Therapies and other high-energy isotopes by clicking the button below to speak to a product specialist directly.